Fosamax
Fosamax (generic name: Alendronate) is in a class of medications used to strengthen bone. Bone is in a constant state of remodeling, whereby old bone is removed by cells called osteoclasts, and new bone is laid down by cells called osteoblasts. Fosamax inhibits bone removal by the osteoclasts.
The safety of Fosamax in patients with significant kidney disease is not known. Therefore, it is not recommended for patients with significant kidney conditions. Since alendronate can lower blood calcium, low blood calcium levels are corrected prior to use. Calcium supplements, antacids and medications can interfere with the absorption of alendronate. The safety and effectiveness of alendronate has not been established in children or women who are pregnant or nursing.
Fosamax side effects
Fosamax Alendronate is generally well tolerated. Side effects are infrequent and mild. Side effects include stomach pain or upset, constipation, diarrhea, muscle ache, and headache. Alendronate can irritate the esophagus to cause heartburn in patients who lie down flat after swallowing, thereby delaying passage of the medication to the stomach.
